Medline IPO: Biggest 2025 Listing Hits Nasdaq at $29

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Dec 17, 2025

Medline just pulled off the biggest IPO of 2025, raising over $6 billion and hitting Nasdaq today. But with heavy debt, tariff pressures from Asia sourcing, and fierce competition, is this medical giant set for smooth sailing—or rough waters ahead?

Financial market analysis from 17/12/2025. Market conditions may have changed since publication.

Imagine a company that’s been quietly powering hospitals and clinics around the world for decades, supplying everything from basic gloves to advanced surgical tools, yet most people have never heard its name. That’s Medline for you—a true behind-the-scenes giant in healthcare. And just yesterday, this Northfield, Illinois-based firm made a splash by going public in what turned out to be the largest initial public offering of 2025.

It’s the kind of move that gets investors buzzing, especially in a year where the IPO market has shown surprising resilience despite some serious headwinds. I always find these big debuts fascinating because they often signal broader confidence in the economy—or at least in certain sectors. In Medline’s case, it’s a bet on the enduring demand for medical essentials.

A Landmark Debut on Nasdaq

Shares of Medline started trading on the Nasdaq under the ticker MDLN, after the company priced its upsized offering at $29 per share. That pricing allowed it to raise an impressive $6.26 billion, making it not just the top IPO in the U.S. this year but globally as well. To put that in perspective, it edges out other notable listings and stands as one of the biggest since the electric vehicle boom a few years back.

The valuation? Around $37 to $39 billion, depending on how you crunch the numbers from the filings. Not bad for a company that started way back in 1966 as a small family operation making aprons and gowns. They’ve come a long way, haven’t they?

We’ve historically done very little advertising or marketing. This IPO gives us a platform to amplify our voice and let more people know who we are.

Jim Boyle, CEO of Medline

The CEO’s comments really drive home the point—this isn’t just about raising cash; it’s about building brand awareness. Medline has often been described as the largest company no one’s heard of, yet its products are in healthcare facilities everywhere.

What Exactly Does Medline Do?

At its core, Medline is a manufacturer and distributor of medical and surgical supplies. Think over 335,000 different products: exam gloves, face masks, scalpels, gowns, wheelchairs, and much more. They serve customers in more than 100 countries, with a massive workforce exceeding 43,000 people as of late last year.

What sets them apart is their end-to-end approach. They don’t just distribute; they produce a lot in-house, including private-label items that help hospitals cut costs. It’s like being the reliable warehouse club for healthcare providers—efficient, vast selection, and focused on value.

  • Extensive product catalog covering all points of care
  • Strong focus on supply chain efficiency and logistics
  • Long-term contracts with high retention rates
  • Global reach with manufacturing in multiple regions

In my view, this vertical integration is a big strength. It allows them to control quality and costs in an industry where reliability can literally be a matter of life and death.

The Private Equity Backstory

Medline’s path to this IPO includes a major chapter involving private equity. Back in 2021, a consortium of heavyweight firms acquired a majority stake in a deal valued at $34 billion—one of the largest leveraged buyouts in years.

Those investors saw huge potential in scaling the business further. And scale they did. Net sales hit $25.5 billion in 2024, with steady growth continuing into 2025. But going private also meant taking on significant debt, which now sits around $16.8 billion.

A chunk of the IPO proceeds is earmarked for paying down that debt—smart move, if you ask me. Reducing leverage can make the company more agile and attractive to long-term shareholders.

Navigating Challenges: Tariffs and Supply Chain Risks

No big story like this is without its hurdles. Medline sources or manufactures a lot of products in Asia, particularly China. Recent trade policies, including broad tariffs, have created uncertainty.

The company has already flagged potential impacts: expecting a $150 to $200 million hit to pre-tax income in the coming fiscal year. Earlier plans for an IPO were even delayed because of this volatility.

It’s a reminder of how global events can ripple through even the most essential industries. Healthcare might be recession-resistant, but it’s not immune to geopolitical tensions or supply disruptions.

The majority of our products come from Asian nations, and tariffs are something we’re monitoring closely.

Still, management seems proactive, diversifying sourcing where possible and leaning on their robust logistics network.

How the IPO Market Fared in 2025

This year has seen over 200 companies go public in the U.S., a solid rebound from slower periods. Despite spring volatility from trade policies and even a prolonged government shutdown, activity held up.

Medline’s success caps off the year on a high note and bodes well for 2026. Investors appear hungry for stable, cash-flow-positive businesses amid uncertainty elsewhere.

  1. Resilient demand in healthcare drives interest
  2. Large deals like this build momentum
  3. Private equity exits provide liquidity
  4. Optimism for even bigger listings ahead

Perhaps the most interesting aspect is how healthcare-focused IPOs have performed. They’re often seen as defensive plays—people need medical supplies no matter what the economy does.

Competition in the Medical Supplies Space

Medline isn’t operating in a vacuum. Big players dominate distribution and manufacturing here.

They go head-to-head with established names that have their own strengths in scale and relationships. Differentiation comes from innovation in private labels, supply chain tech, and customer service.

With public status, Medline gains more visibility to win bigger contracts or even pursue acquisitions. That’s exciting potential.

Key MetricMedline (2024)Industry Context
Net Sales$25.5 billionLeading position globally
EmployeesOver 43,000Massive operational scale
Product SKUs335,000+Unmatched variety
Debt Level$16.8 billionTarget for reduction post-IPO

This snapshot highlights why investors are intrigued. The numbers are substantial, and the market is growing with aging populations and expanding healthcare access worldwide.

What Investors Should Watch Next

As trading begins, all eyes will be on how shares perform in the early days. Will there be a pop, or a more measured start? Longer term, key things include:

  • Progress on debt reduction and balance sheet health
  • Impact of any ongoing trade policies
  • Growth in sales and margins
  • Ability to leverage public status for expansion
  • Overall sentiment in healthcare stocks

I’ve found that companies like this, with strong fundamentals in essential sectors, often reward patient investors. But nothing’s guaranteed—markets can be fickle.

One question that lingers for me: Can Medline maintain its growth streak while navigating these challenges? They’ve done it for decades privately; now the spotlight is on.


In the end, this IPO feels like a vote of confidence in healthcare’s stability. Medline’s story is one of quiet dominance finally stepping into the light. Whether you’re considering the stock or just watching the market, it’s a development worth following closely. The coming quarters will tell us a lot about where this giant heads next.

And who knows—maybe in a few years, Medline won’t be the biggest company you’ve never heard of anymore.

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— Sir John Templeton
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